About

A global network of IBD consortia

The International Inflammatory Bowel Disease Genetics Consortium (IIBDGC) is a global network of hundreds of researchers from > 20 countries across four continents.

The mission of the IIBDGC is to (1) identify the genetic risk factors for the inflammatory bowel diseases (IBD), Crohn’s disease (CD), ulcerative colitis (UC), and related clinical phenotypes, (2) to determine how these risk factors interact with non-genetic risk factors impact on an individual’s risk to develop IBD, CD, UC and related phenotypes, (3) perform these studies in a collaborative fashion and to broadly share the results with the international scientific community in a responsible fashion.

Our current projects bring together genome-wide genotyping data and whole exome/whole genome sequencing data for over 75,000 patients with IBD. For more information on how to join the IIBDGC, please consult our Memorandum of Understanding (MOU).

Groups involved

We extend an open invitation to any group that wishes to join our consortium. If you are interested in joining the consortium please contact contact@ibdgenetics.org.

Members of the IIBDGC collectively sign a shared MOU.

Members

Regional Consortia

Signatory Investigators
Name Affiliation
Aarno Palotie Institute for Molecular Medicine Finland
Andre Franke Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University of Kiel
Anna Latiano Fondazione IRCCS Casa Sollievo della Sofferenza, Gastroenterology Unit
Antonio Julià Rheumatology Research Group, Vall d’Hebron University Hospital, Barcelona, Spain
Bruce Sands Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai
Caren Heller Crohn’s & Colitis Foundation
Charles Bernstein University of Manitoba IBD Clinical and Research Centre
Christopher Moran MassGeneral Hospital for Children
David Okou Emory University
Denis Franchimont Department of Gastroenterology, Erasme Hospital, Free University of Brussels, Belgium
Dermot Mcgovern Cedars-Sinai
Edouard Louis CHU Liège
Gerhard Rogler Department of Gastroenterology and Hepathology
Graham Radford-Smith QIMR Berghofer MRI
Hailiang Huang Broad Institute
Hakon Hakonarson Children’s Hospital of Philadelphia
Hamed Khalili Massachusetts General Hospital Gastroenterology Unit
Harry Sokol St Antoine Hospital, APHP
Jacob Mccauley John P. Hussman Institute for Human Genomics, Leonard M. Miller School of Medicine, University of Miami
Jean-Paul Achkar Cleveland Clinic
Joel Pekow University of Chicago
John Rioux Montreal Heart Institute, Research Center
Jonas Halfvarson Dept. Of Gastroenterology, Faculty of Medicine and Health, Örebro University
Judith Kelsen Children’s Hospital of Philadelphia
Judy Cho Icahn School of Medicine at Mount Sinai
Juozas Kupcinskas Department of Gastroenterology, Lithuanian University of Health Sciences
Lee A Denson Cincinnati Children’s Hospital Medical Center
Luis Bujanda Osakidetza-Basque Health Service
Lynnette R Ferguson The University of Auckland
Manuel Rivas Stanford University
Maria Abreu Division of Gastroenterology, Department of Medicine, Leonard M. Miller School of Medicine, University of Miami
Mark Daly The Broad Institute
Mark Silverberg Mount Sinai Hospital, Toronto ON
Miles Parkes Addenborookes Hospital
Ramnik Xavier Broad Institute
Reza Malekzadeh DDRI, Tehran University of Medical Sciences
Richard Gearry Department of Medicine, University of Otago, Christchurch
Richard H. Duerr Department of Medicine, University of Pittsburgh School of Medicine
Rinse K. Weersma Dept of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, The Netherlands
Siew Chien Ng The Chinese University of Hong Kong
Steven Brant Rutgers University
Subramaniam Kugathasan Emory University
Séverine Vermeire Department of Gastroenterology - University hospitals Leuven
Tim Orchard Imperial College London
Uroš Potočnik University of Maribor, Faculty of Medicine, Center for Human Molecular Genetics and Pharmacogenomics
Vibeke Andersen Focused Research Unit for Molecular Diagnostic and Clinical Research, Hospital of Southern Jutland

Downloads

Datasets

Old

Documents

MOU Instructions:

  1. Complete the MOU Web Form.
  2. Sign the received copy of the completed form at your provided email address.
  3. Send the signed copy to contact@ibdgenetics.org.

DUA Instructions:

All individuals seeking to access pre-publication summary statistics need to submit a signed DUA
  1. Download the form here.
  2. Complete the document using a pdf editing tool (e.g. adobe acrobat, apple preview).
    1. Initial the “IIBDGC Internal Use Only” appendix if applicable (i.e. when requesting access to pre-publication data).
  3. Send the signed copy to requests@ibdgc.org.
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Publications

Explore all publications with the search function.
Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility
Abstract Genome-wide association studies (GWAS) have identified hundreds of loci associated with Crohns disease (CD), however, as with …
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Contact

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